Risk of Developing Type 1 Diabetes

Risk of Developing Type 1 Diabetes

The CDC predicts that 37.3 million Americans have diabetes, making it one of the most common chronic diseases in the United States. Out of these people, 1.45 million have type 1 diabetes. 

Type 1 diabetes is a chronic autoimmune disease where your pancreas can’t produce insulin. As a result, those with the illness must perform daily management for blood sugar monitoring and insulin injection. 

Because it’s a disease many people in the States have, it’s essential to know the risk of developing type 1 diabetes. Understanding this can help prevent its more severe effects and damage. 

Risk factors for type 1 diabetes

photo of a medical professional passing a continuous glucose monitor to a patient

Type 1 diabetes (also known as insulin-dependent diabetes) is a genetically-driven disease. Therefore, the three primary risk factors of this illness include: 

  • Age – Type 1 diabetes can occur at any age. However, it generally develops in younger adults and children. 
  • Genetics – Certain genes might increase the likelihood of developing type 1 diabetes (known as HLA-DQA1, HLA-DQB1, and HLA-DRB1). A doctor can test for these genes.
  • Family history – Having close family members with type 1 diabetes raises the chance of getting the disease. The risk increases if both parents have type 1 diabetes.

As seen, the risk of developing type 1 diabetes is limited. Unlike type 2 diabetes, type 1 isn’t developed from lifestyle choices. Anybody is susceptible to type 1, regardless of their healthy, active lifestyle. 

What causes type 1 diabetes

Insulin-dependent diabetes occurs when your immune system mistakenly targets and eliminates insulin-producing cells in your pancreas. This destruction can unfold over months or years, eventually leading to insulin deficiency.

Although scientists are unsure of the origin of Type 1 diabetes, they believe it has a significant genetic component. A study produced by Pediatr Diabetes suggests that the general risk of this disease is 0.4%. However, children with type 1 diabetes have an average lifetime risk of 6-7%.

But we must note that it’s well-documented that scientists have mentioned that environmental chemicals (Air pollution, tobacco smoke, etc.) might trigger or accelerate the development of type 1 diabetes.

Is type 1 diabetes preventable?

Though scientists are working on ways to slow down or prevent the progression of insulin-dependent diabetes, it’s still undiscovered. Therefore, you can do little to avoid Type 1 diabetes. 

However, there are methods to reduce the severity of the illness:

  • Monitoring and managing your blood sugar levels effectively 
  • Following your doctor’s advice on how to live a healthy lifestyle
  • Getting regular health check-ups that showcase your overall wellness and seeking improvement 

These are the only ways to decrease the damage of type 1 diabetes. But remember, it will never prevent it. 

Additionally, if you’re diagnosed with type 1 diabetes, you must get educated on self-management. Knowing about the disease can undoubtedly reduce the risks involved.

Conclusion

After reading the above, you should understand the risk of developing type 1 diabetes. As you now know, this disease is genetically driven. Therefore, it’s more likely to affect those that already have the illness in the family. 

If you’d like to learn more about becoming a pioneer in diabetes research you can check out our current studies at the link below.

Be a pioneer for diabetes research!

We are looking for healthy adults to take part in a paid insulin research study for diabetes in San Diego, California. You will earn financial payment up to $2,300 if all study visits are completed. Health insurance is not needed to participate.

If this is something you’re interested in, we encourage you to click the “sign up” button. The form should take less than a minute to complete.

Start the process today! During your 1-on-1 call, we’ll get more health information from you. We will use this information to find out if you are eligible for this study or any other paid and actively enrolling research studies at our research center.

You May Qualify If You Are:

Between 18 and 65 years old

Study Details

Up to 4 visits

Up to $2,300

Sign Up Today!

To join this paid research study, you will need to complete an easy and risk-free, 20-minute phone questionnaire about you and your current health status. We will use this information to find out if you are eligible for this study or any other paid and actively enrolling research studies at our research center.

Email: 
First Name: 
Last Name: 
Phone Number: 
Which of the following applies to you?

Are you taking/prescribed any of the following types of medications?

Acerca de este estudio de investigación pagado

ProSciento está buscando adultos con diagnóstico de diabetes tipo 2 para participar en un estudio de investigación remunerado en San Diego, CA

No es necesario tener seguro médico para participar. ¡Comience el proceso hoy mismo! 

Para participar en este estudio de investigación remunerado, deberá completar un cuestionario telefónico sencillo de 20 minutos sobre usted y su estado de salud actual.

Usaremos esta información para averiguar si es elegible para este estudio o para cualquier otro estudio de investigación remunerado y con inscripción abierta en nuestro centro de investigación.

Nos complace responder a cualquier pregunta que pueda tener, y le proporcionaremos todos los detalles sobre el estudio durante su llamada telefónica con nuestro equipo de atención médica atento y altamente capacitado.

Puede reunir los requisitos si cumple las siguientes condiciones:

  • Es adulto y tiene diabetes tipo 2
  • Tiene entre 30 y 70 años

Detalles del estudio:

Hasta 4 visitas

Hasta $7,925

scroll to apply

Sign Up Today

To join this paid research study, you will need to complete an easy and risk-free, 20-minute phone questionnaire about you and your current health status. We will use this information to find out if you are eligible for this study or any other paid and actively enrolling research studies at our research center.


Get To Know Us

ProSciento’s clinical research facility is located 10 miles south of San Diego’s downtown area, 13 miles south of the San Diego International Airport, and 7 miles north of the US/Mexico border.

An on-site parking lot and parking garage are available and located within convenient access to public transportation. Additional transportation options may also be available at no-cost to you.

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Suite 4400,
Chula Vista, CA 91911

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7 a.m. – 6 p.m.

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About This Paid Research Study

We are partnering with City of Hope® to look for adults living with Type 1 Diabetes to take part in their
research study to evaluate an experimental personalized immunotherapy (vaccine) for type 1 diabetes. All
study activities will take place at City of Hope® campus in Duarte, California.

The PIpepTolDC vaccine is a type of immunotherapy (a treatment that uses a person’s own immune system). The vaccine is made using your own immune cells and a beta cell protein. The vaccine may help your beta cells recover and make enough insulin to control your blood sugar levels. The vaccine may also help reduce future type 1
diabetes-related complications.

You’ll need to complete a risk-free, 20-minute phone call with one of our team members to see if you are
eligible. No health insurance is needed to participate!

You May Qualify If You Are:

  • Between 18 and 45 years old
  • An adult who has known antibodies or a history of antibodies
  • An adult living with type 1 diabetes for 1-4 years

Study Details:

Up to 2 years

Up to $1,500

scroll to apply

Sign Up Today

To join this paid research study, you will need to complete an easy and risk-free, 20-minute phone questionnaire about you and your current health status. We will use this information to find out if you are eligible for this study or any other paid and actively enrolling research studies at our research center.


Get To Know Us

ProSciento’s clinical research facility is located 10 miles south of San Diego’s downtown area, 13 miles south of the San Diego International Airport, and 7 miles north of the US/Mexico border.

An on-site parking lot and parking garage are available and located within convenient access to public transportation. Additional transportation options may also be available at no-cost to you.

Home Icon

Visit Us

855 3rd Avenue,
Suite 4400,
Chula Vista, CA 91911

Phone Icon

Call Us

1-866-308-7427

Hours (PST)
Monday – Friday
7 a.m. – 6 p.m.

Email Icon

Contact Us

hello@myproscientostudy.com

About This Paid Research Study

If you are overweight, you may qualify to participate in a clinical research studyVolunteers may receive a stipend up to $4,150 for their time Your participation could last approximately 32 weeks and include up to two (4-day) in-house staysYou may also be considered for future research studies at ProSciento. Our research facility is located in Chula Vista, California. 

This study is to evaluate a new investigational medication being developed as a new option for people with Non-Alcoholic Steatohepatitis (NASH) who carry a specific gene we are looking to identify.

You May Qualify If You Are:

  • Currently overweight
  • Between 18 and 75 years old

Study Details:

Up to 32 weeks

Up to $4,150

scroll to apply

Sign Up Today

To join this paid research study, you will need to complete an easy and risk-free, 20-minute phone questionnaire about you and your current health status. We will use this information to find out if you are eligible for this study or any other paid and actively enrolling research studies at our research center.


I acknowledge that ProSciento may use my personal information in accordance with its Privacy Policy.

Get To Know Us

ProSciento’s clinical research facility is located 10 miles south of San Diego’s downtown area, 13 miles south of the San Diego International Airport, and 7 miles north of the US/Mexico border.

An on-site parking lot and parking garage are available and located within convenient access to public transportation. Additional transportation options may also be available at no-cost to you.

Home Icon

Visit Us

855 3rd Avenue,
Suite 4400,
Chula Vista, CA 91911

Phone Icon

Call Us

1-866-308-7427

Hours (PST)
Monday – Friday
7 a.m. – 6 p.m.

Email Icon

Contact Us

hello@myproscientostudy.com

About This Paid Research Study

If you’ve been diagnosed with type 2 diabetesyou may qualify to participate in a clinical research studyVolunteers may receive a stipend up to $4,150 for their time Your participation could last approximately 32 weeks and include up to two (4-day) in-house staysYou may also be considered for future research studies at ProSciento. Our research facility is located in Chula Vista, California. 

This study is to evaluate a new investigational medication being developed as a new option for people with Non-Alcoholic Steatohepatitis (NASH) who carry a specific gene we are looking to identify.

You May Qualify If You Are:

  • An adult living with type 2 diabetes
  • Between 18 and 75 years old

Study Details:

Up to 32 weeks

Up to $4,150

scroll to apply

Sign Up Today

To join this paid research study, you will need to complete an easy and risk-free, 20-minute phone questionnaire about you and your current health status. We will use this information to find out if you are eligible for this study or any other paid and actively enrolling research studies at our research center.

Get To Know Us


ProSciento’s clinical research facility is located 10 miles south of San Diego’s downtown area, 13 miles south of the San Diego International Airport, and 7 miles north of the US/Mexico border.

An on-site parking lot and parking garage are available and located within convenient access to public transportation. Additional transportation options may also be available at no-cost to you.

Home Icon

Visit Us

855 3rd Avenue,
Suite 4400,
Chula Vista, CA 91911

Phone Icon

Call Us

1-866-308-7427

Hours (PST)
Monday – Friday
7 a.m. – 6 p.m.

Email Icon

Contact Us

hello@myproscientostudy.com

Clinical Trials and What You Should Know

Clinical Trials and What You Should Know

Clinical trials are how researchers test new investigational medicines or treatments before they are widely available to patients.  People like you participate in clinical trials every day. Some because they have limited treatment options and others because they know someone with an untreatable condition. Whatever the reason, these individuals are all contributing their time to help expand treatments in the future.

The goal of a clinical trial is to collect information on the safety and efficacy effectiveness of a drug. Every new drug or treatment must complete the clinical trial process before being submitted for Food and Drug Administration (FDA) approval.  By participating in the clinical development, you are gaining access and contributing to potential new therapeutics and technologies not yet available in the market. You are supporting medical and scientific progress and success, which may be of great benefit to those affected.

Let’s take a closer look…

What is a Clinical Trial?

Clinical trials are how researchers test new investigational medicines or treatments before they are widely available to patients. Clinical trials are conducted in phases.  

Photo of a doctor talking to a patient

The decision to join a clinical trial is a personal decision. We encourage you to consult with your doctor, talk to your family, and ask questions.

There are three to four phases that must be completed before a new medication or treatment is approved by the FDA and each phase has a specific purpose.

    • Phase 1 is tested on a small group of usually healthy study participants to test safety and dosage limitations. 
    • Phase 2 involves a larger group of study participants and seeks to determine if a drug is effective in people with specific medical conditions. Safety and side-effects are monitored, and this phase may extend for several years. 
    • Phase 3 involves an even greater amount of study participants and continues to gather information on safety and effectiveness. If the results of Phase 3 are positive, the study treatment will be submitted for approval to the FDA. 
    • Phase 4 studies are conducted if additional research questions need to be answered. Phase 4 studies are conducted after FDA approval when the treatment is already available to the public. This phase tests the long-term effectiveness and side effects of the new treatment over a large population in real life scenarios.

Every clinical trial is guided by a study protocol (plan) that is reviewed for safety and designed to answer specific research questions.

When you are offered an opportunity to join a trial, the purpose of the study, tests and procedures conducted, and medications you will be taking will be clearly explained. Potential benefits and risks will also be explained by clinical research staff before you consent to participate in any trial.

ProSciento’s team of experts manages clinical research studies domestically and internationally. If you’d like to learn more about clinical research studies, or what we do, please call [#]. Once you get on a call with our trained healthcare team, we can answer any questions and/or concerns you may have.

Whatever your motivation for joining a clinical trial, you can be confident that you are in great company! Most drugs available in the market today were only made possible by study participants.

Conclusion

Clinical trial researchers partner with study participants to help advance science in the treatment of diseases.

Before enrolling in a study, we encourage you to talk to your family and consult with your doctor about any questions you may have. When you’re ready, one of our highly trained team members will guide you through the process every step of the way. We have English and Spanish-speaking team members ready to help you and answer any questions or concerns you may have.

Diabetes: What happens if left untreated?

The Progression of Diabetes

Diabetes is a progressive disease and making some simple choices can drastically change your outcome if addressed early. Ignoring type 2 diabetes is life-threatening!  Talk to your doctor and manage your type 2 diabetes to live a long and healthy life!

Unmanaged type 2 diabetes leads to: 

    • Fat build-up in your liver also known as fatty liver disease 
    • Eye diseases like cataracts and glaucoma, retinopathy, possibly blindness 
    • Nerve damage and skin infections that may require limb amputation 
    • Heart damage doubling the risk of heart attack and stroke 
    • Kidney damage requiring regular dialysis and possibly a transplant  
    • Irreversible erectile dysfunction 
    • Dental problems such as gum disease and mouth ulcers 
    • Increased odds of getting Alzheimer’s disease 

 

Let’s Break Down The Information…

Untreated diabetes

How common is diabetes?

Diabetes is a progressive disease and making some simple choices can drastically change your outcome if addressed early. Ignoring type 2 diabetes is life threatening! 

Infographic of a breakdown of diabetes

Eating healthy while keeping track of your BMI and A1C can help reduce your risk of complications related to diabetes!

Clinical trial researchers partner with study participants to help advance science in the treatment of diseases.

Before enrolling in a study, we encourage you to talk to your family and consult with your doctor about any questions you may have. When you’re ready, one of our highly trained team members will guide you through the process every step of the way. We have English and Spanish-speaking team members ready to help you and answer any questions or concerns you may have.

Obesity & Diabetes: What’s the connection?

Clinical Trials and What You Should Know

Obesity does increase the likelihood of an individual to develop type 2 diabetes. A common understanding of medicine is that being overweight or obese is a precursor to type 2 diabetes. An obese body can create insulin, but the cells develop a resistance to it, known as prediabetes.

Your body will keep producing elevated levels of insulin as compensation for lower glucose cell absorption. This results in elevation of blood glucose levels, which greatly increases the probability of type 2 diabetes.  The good news is that obesity and type 2 diabetes are preventable with a proper diet and regular exercise.

Let’s Break Down The Information…

Obesity

How common is obesity?
A study conducted by the Centers for Disease Control and Prevention (CDC) in 2017-2018 found that 42.4% of American adults are obese.

Photo of a doctor talking to a patient

The study defines obesity as a Body Mass Index (BMI) greater than or equal to 30. The incidence of diabetes and obesity relate based on BMI and age.

As you age, the chances of becoming diabetic increase steadily. If you are obese, the risk of a diabetes diagnosis multiplies. The threat in obese women is more than double that of men in all age ranges.

Insulin Resistance

An obese body can create insulin, but the cells develop a resistance to it, known as prediabetes.

Insulin resistance is when cells in your muscles, fat, and liver do not respond well to insulin and cannot easily take up glucose from your blood. As a result, your pancreas makes more insulin to help glucose enter your cells. As long as your pancreas can make enough insulin to overcome your cells’ weak response to insulin, your blood glucose levels will stay in the healthy range.

Know Your Numbers

The accurate measure of your diabetic risk is to know your numbers. Many overweight people do not believe they are obese and are in danger of becoming diabetic. Tracking your BMI is more important than the numbers on a bathroom scale. To measure your BMI, we suggest the following link: https://www.nhlbi.nih.gov/health/educational/lose_wt/BMI/bmicalc.htm

The other number you need to know is your A1C. A1C is a measurement of your average blood glucose levels over three months. The CDC has determined that a normal A1C is below 5.7%. With a result up to 6.4%, you are considered prediabetic and diabetic above that range.

The numbers do not lie, and you can only improve what you track.

What Can I Do?

The good news is that obesity and type 2 diabetes are preventable with a proper diet and regular exercise.

According to the American Diabetes Association, physical activity promotes an increase in insulin sensitivity, which can reverse your insulin resistance, and losing approximately 10-15 pounds will impact your health significantly.

Remember, the numbers do not lie, and you can only improve what you track.

Conclusion and Closing Thoughts

Eating healthy while keeping track of your BMI and A1C can help reduce your risk of getting diabetes!

During these unprecedented times, your diabetes may have improved or worsened. At ProSciento, we will test your HbA1c at no cost as part of study screening. Schedule your appointment today!

Nutrition and Healthy Eating Information

Nutrition and Healthy Eating Information

About ProSciento’s Research Nutrition Department

A Registered Dietitian Nutritionist (RDN) is an expert in the use of food and nutrition to promote health. At ProSciento, our RDNs are responsible for providing nutritionally balanced meals for our study participant’s well-being and enjoyment while also maintaining the integrity of each research study. 

Our Research Nutrition team works hard to put together the best meals possible for you! Some studies have specific food requirements, but our meals are always meant to be nutritious while also appealing to a wide range of cultural and taste preferences. 

Upon request, meal accommodations may be made if they are within the protocol requirements and within the capabilities of the Research Nutrition Department. Possible accommodations may include vegetarian, vegan, dairy free, and gluten-free meal options. 

Celiac Sprue disease will be assessed individually by our study team prior to entry into a research study. This is to ensure that you are safe throughout your study participation.

Our Research Nutrition team creates daily menus based on the requirements for each study. Unless a study specifies otherwise, snacks may be included between meals. 

While participating in one of our studies all meals will be provided at no cost to you! If you have specific meal requirements, please let us know during your phone appointment so we may ensure you get the correct menu during your stay.

See what types of meals and foods are served during a research study: [link]

Good nutrition is about having a well-rounded diet.

There are many ways to eat healthy! Making smart food choices can help you manage your weight and lower your risk for some long-term diseases. 

Eating healthy doesn’t look the same for everyone! It’s important to find a balance that’s right for you and meets your nutritional and lifestyle needs. Restrictive diets are not always the answer. Talk to your doctor to learn more about healthy food choices that are right for you. 

Here are our top 5 healthy eating tips:

  • Pick a variety of colors for your plate.
      1. Choose brightly colored fruits and vegetables each day, orange and dark green vegetables are a great choice.
      2. Foods like dark, leafy greens, oranges, and tomatoes—even fresh herbs—are loaded with vitamins, fiber, and minerals.
  • Choose whole grain foods
      1. Replacing refined grains with whole grains is can significantly improve your health. Examples of whole grains include brown rice, 100% whole wheat bread, quinoa, barley, buckwheat, and oatmeal.
      2. Whole grains reduce risks of heart disease, stroke, cancer, diabetes, and obesity. Few foods can offer such diverse benefits.
  • Lower sodium intake
      1. Good nutrition is about balance, and that means not getting too much of certain ingredients, such as sodium (salt). Sodium increases blood pressure, which raises the risk for heart disease and stroke.
  • Avoid highly and ultra-processed foods
      1. Processed foods such as frozen meals, ready-to-eat meals, baked goods, and processed meats can be high in sugar, artificial ingredients, refined carbohydrates, and trans fats and can have negative health effects. 
      2. Read food labels. Highly and ultra-processed foods tend to have a long ingredient list with additives like artificial flavors, added sugars, stabilizers, preservatives and more. 
      3. Prepare most of your meals at home using whole or minimally processed foods. 
  • Make water your drink of choice
    1. Avoid sugary drinks and instead drink water. Sugary drinks packed with sugar provide many calories but virtually no other nutrients.
    2. Keep a reusable water bottle in your purse or car so you can fill up wherever you are going.
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